LETROMED – Human Labs

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💊 Letrozole for Fertility – LETROMED Human Labs

Letrozole is a non-steroidal aromatase inhibitor that lowers estrogen levels by blocking the enzyme aromatase.
While approved as a breast cancer treatment in postmenopausal women (PharmaWiki), it is also widely prescribed off-label for fertility treatment – especially in women with ovulation disorders such as PCOS.

⚕️ How Letrozole Helps Fertility

By reducing estrogen levels, letrozole increases the release of FSH (follicle-stimulating hormone), which stimulates ovulation.
This mechanism makes it an alternative to clomiphene for women who do not respond to standard fertility treatments.

📈 Medical Use & Dosage

  • Standard medical use: treatment of hormone-sensitive breast cancer in postmenopausal women
  • Off-label use: fertility treatment to induce ovulation
  • Typical dosage: once daily tablet at the same time, independent of meals (PharmaWiki)

⚠️ Side Effects & Risks

Side effects are mainly due to reduced estrogen levels:

  • 🔥 Hot flashes & sweating
  • 🦴 Joint pain
  • 💤 Fatigue & weakness
  • ⬆️ Hypercholesterolemia
  • 🚫 Contraindications: pregnancy, breastfeeding, premenopausal women

❌ Misuse Warning

Letrozole is sometimes misused as a doping agent in bodybuilding to reduce estrogen.
Such use is banned in and outside competitions and carries health risks.

❓ FAQ – Letrozole for Fertility

1. How effective is letrozole for fertility?
👉 Clinical studies show that letrozole can induce ovulation and improve pregnancy rates in women with PCOS.

2. Is letrozole safe during pregnancy?
👉 ❌ No. Letrozole must not be taken during pregnancy or breastfeeding.

3. How long is letrozole treatment?
👉 Typically 5 days per cycle under medical supervision.

📚 References & Sources

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