š Definition
Letrozole is a targeted hormone therapy for breast cancer.
As a result, it lowers estrogen levels by blocking the aromatase enzyme, slowing cancer growth and reducing recurrence risk.
š Brand vs Generic
Letrozole is available as a generic and under the brand name Femara.
Generally, generics are identical in efficacy and safety but often cost less.
š Learn more about generic vs. brand: Healthline ā Generic vs. Brand.
āļø Pharmacology
Letrozole tablets work by binding to the aromatase enzyme and preventing estrogen synthesis.
Consequently, estrogen-dependent cancer cells lose their growth stimulus.
Additionally, letrozole has a long half-life, which supports once-daily dosing.
ā ļø Side Effects
- Hot flashes and sweating
- Joint and muscle pain
- Osteoporosis or bone thinning
- Fatigue and dizziness
- Cholesterol changes
Therefore, monitoring bone density and cardiovascular health is recommended during therapy.
š„ Indications
Doctors prescribe letrozole for different stages of breast cancer, including:
- Early breast cancer (hormone receptor positive, after surgery)
- Locally advanced breast cancer
- Metastatic breast cancer (spread beyond breast/lymph nodes)
š More info: Medical News Today ā HR+ Breast Cancer.
š« Legal & Prescription Status
Letrozole is a prescription-only drug worldwide.
Consequently, it cannot be bought legally without medical approval.
However, online searches for letrozole cost usually compare pharmacies and generic versions.
š References
- Healthline ā Letrozole Oral Tablets
- Healthline ā Femara
- Healthline ā Breast Cancer Overview
- Healthline ā Menopause
- American Cancer Society ā Hormone Therapy
ā Frequently Asked Questions (FAQ)
What is Letrozole used for?
Letrozole treats hormone-receptor-positive breast cancer in postmenopausal women.
š It reduces estrogen levels and lowers recurrence risk.
How much does Letrozole cost?
The letrozole cost depends on brand vs. generic.
In general, generic letrozole is significantly cheaper than Femara.
Is Letrozole safe to use long-term?
Yes, but long-term use may cause side effects such as osteoporosis or joint pain.
Therefore, patients should be monitored with regular check-ups.
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