📖 Definition
Methenolone Enanthate is an anabolic-androgenic steroid (AAS), available as an intramuscular injection.
It belongs to the class of Dihydrotestosterone (DHT) derivatives and is known for promoting lean muscle growth without excessive water retention or estrogenic side effects.
📜 History
Methenolone was introduced in the early 1960s by the pharmaceutical company Schering.
It was marketed under the brand name Primobolan (acetate form, oral) and Primobolan Depot (enanthate form, injectable).
Initially developed to treat anemia and wasting syndromes, it eventually gained popularity among athletes and bodybuilders for performance enhancement.
💊 Medical Use
Clinically, Methenolone Enanthate has been used for treating anemia, muscle wasting diseases, and osteoporosis.
It helps preserve muscle mass during illness, aging, or recovery.
However, its medical use has largely declined due to stricter regulations and the development of safer alternatives.
⚗️ Pharmacology
Primobolan acts as an androgen receptor agonist, enhancing protein synthesis and nitrogen retention.
Unlike many AAS, it does not aromatize into estrogen, meaning no water retention or gynecomastia.
With a half-life of about 10 days, it allows for weekly injections.
Its anabolic activity is moderate, while androgenic activity remains low.
🏋️ Bodybuilding Use
In bodybuilding, methenolone enanthate is considered a safe choice for cutting and lean bulking cycles.
A typical dosage ranges from 400–800 mg per week for men.
Women may use 50–100 mg per week, though the risk of virilization exists.
Moreover, it is commonly stacked with testosterone, drostanolone, or trenbolone for enhanced results.
⚠️ Side Effects
While relatively mild, side effects can still occur:
- Acne and oily skin
- Hair loss in predisposed individuals
- Suppression of natural testosterone
- Virilization in women (deepened voice, hair growth)
- Altered cholesterol levels (lipid strain)
Nevertheless, methenolone is less hepatotoxic compared to many oral steroids and considered one of the safer AAS options.
🚫 Legal Status
Methenolone Enanthate is a controlled substance in the US, UK, Canada, and most of Europe.
Consequently, possession without prescription is illegal, and its use in competitive sports is banned by the World Anti-Doping Agency (WADA).
📚 References
❓ Frequently Asked Questions (FAQ)
What is Methenolone Enanthate?
It is an anabolic steroid (Primobolan Depot) used to promote lean muscle retention and improve recovery during cutting cycles.
Is Methenolone Enanthate safe?
Compared to other steroids, it has a mild profile, but it can still suppress testosterone and affect cholesterol.
Medical supervision is recommended.
Does Methenolone Enanthate cause water retention?
No. Since it does not aromatize into estrogen, it does not cause bloating or gynecomastia.
How is Methenolone Enanthate used?
It is injected intramuscularly, typically once per week, with cycles lasting 8–12 weeks.
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