MAST E 200 Human Labs – What is Drostanolone Enanthate?

Drostanolone Enanthate is a synthetic anabolic-androgenic steroid (AAS) derived from
dihydrotestosterone (DHT).
Originally introduced in the 1960s under trade names such as Masteron, it was first used in the treatment of
breast cancer.
Today, medical use is rare, but in bodybuilding, drostanolone enanthate is highly popular for cutting phases
because of its ability to increase muscle hardness without water retention.

Pharmacology of Drostanolone Enanthate

Pharmacokinetics

As the enanthate ester, drostanolone has a long half-life of around 7–10 days.
It is administered intramuscularly
in an oil solution. After injection, the ester is slowly released and hydrolyzed into active drostanolone,
allowing for fewer injections compared to shorter esters like propionate
(Wikipedia Source).

Pharmacodynamics

Drostanolone binds to the androgen receptor
with strong affinity, enhancing nitrogen retention and protein synthesis. Unlike testosterone,
it cannot be aromatized to estrogens, which means there is virtually no risk of
gynecomastia.
This makes it a preferred choice for athletes aiming for a lean, hard, and dry look.

Dosage & Cycle

• 👤 Beginners: 200–300 mg per week
• 🏋️ Intermediate: 400–500 mg per week
• 🔥 Advanced: 600–800 mg per week, often stacked with Trenbolone, Testosterone, or Winstrol
• ⏳ Cycle length: 8–12 weeks

Because natural testosterone production is suppressed, athletes should plan a Post-Cycle Therapy (PCT)
with Clomid or Nolvadex after discontinuation.

Medical Indications

Drostanolone was originally used for:

• Treatment of advanced breast cancer
• Hormone-related disorders (historic use)

Today, its medical role is negligible, and it is primarily a performance-enhancing drug.

Possible Side Effects

• ⚠️ Hair loss (male pattern baldness)
• ⚠️ Acne and oily skin
• ⚠️ Increased aggression and mood swings
• ⚠️ Suppression of natural testosterone production
• ⚠️ Adverse changes in cholesterol and blood pressure
• ⚠️ Deepened voice and body hair growth (in women)

Despite being non-hepatotoxic, misuse can still pose serious health risks.